DTWD2

Across TCGA patient cohorts, DTWD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,605 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DTWD2-associated proteins across cancer lineages are CYRIA, HSD17B4, and HSPA4. Each is linked with DTWD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DTWD2-to-partner and partner-to-DTWD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTWD2 versus CYRIA in UCEC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD2→partner) and Y-score (partner→DTWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYRIA →	-0.383	-0.606	.001	.003	3	4
BRCA	HSD17B4 →	+0.461	+0.705	<.001	<.001	3	4
OV	HSPA4 →	+0.245	+0.417	.001	<.001	3	4
BRCA	NUDCD2 →	+0.472	+0.792	<.001	<.001	3	4
OV	YTHDC2 →	+0.429	+0.599	<.001	<.001	3	4
OV	PPIP5K2 →	+0.242	+0.388	.005	.008	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,605 associations by consensus.

DTWD2 vs CYRIA — UCEC

Explore this scatter interactively →