DTWD2

Across TCGA patient cohorts, DTWD2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,646 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DTWD2-associated genes across cancer lineages are APOBEC3A, NDUFA2, and HSD17B4. Each is linked with DTWD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DTWD2-to-partner and partner-to-DTWD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTWD2 versus APOBEC3A in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD2→partner) and Y-score (partner→DTWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOBEC3A →	-0.794	-0.334	.002	.003	3	4
UCEC	NDUFA2 →	+0.700	+0.216	.004	.001	3	4
UCEC	HSD17B4 →	+0.636	+0.292	<.001	<.001	3	4
BRCA	RNF14 →	+0.620	+0.571	<.001	<.001	3	4
UCEC	TIGD6 →	+0.375	+0.219	.007	.002	3	4
UCEC	CES2 →	+0.711	+0.244	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,646 associations by consensus.

DTWD2 vs APOBEC3A — BRCA

Explore this scatter interactively →