DTWD2

Across TCGA cell cohorts, DTWD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,351 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DTWD2-associated GO terms across cancer lineages are CAAX-box protein maturation, Establishment of protein localization to organelle, and Regulation of formation of translation preinitiation complex. Each is linked with DTWD2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DTWD2-to-partner and partner-to-DTWD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAAX-box protein maturation grouped by DTWD2-low versus DTWD2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD2→partner) and Y-score (partner→DTWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	CAAX-box protein maturation →	+0.122	+0.806	.001	.001	3	13
OESOPHAGUS	Establishment of protein localization to organelle →	+0.086	+1.022	<.001	.004	3	12
LARGE_INTESTINE	Regulation of formation of translation preinitiation complex →	+0.075	+0.678	<.001	.003	3	10
LARGE_INTESTINE	Negative regulation of formation of translation preinitiation complex →	+0.075	+0.678	<.001	.003	3	10
URINARY_TRACT	Negative regulation of mitotic cell cycle phase transition →	+0.046	+0.508	.001	.002	3	10
PANCREAS	Negative regulation of cell cycle process →	+0.046	+0.754	.005	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,351 associations by consensus.

CAAX-box protein maturation by DTWD2 expression — LIVER

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