DTWD1

Across TCGA patient cohorts, DTWD1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,376 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTWD1-associated genes across cancer lineages are PDCD7, BUB1B, and RAD51. Each is linked with DTWD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DTWD1-to-partner and partner-to-DTWD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTWD1 versus PDCD7 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD1→partner) and Y-score (partner→DTWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDCD7 →	+0.354	+0.296	.002	<.001	3	4
OV	BUB1B →	+0.966	+0.375	<.001	<.001	3	4
GBM	RAD51 →	+0.783	+0.456	.002	<.001	3	4
GBM	TEX9 →	+0.683	+0.490	.001	<.001	3	4
BRCA	CERK →	+0.436	+0.273	.002	.001	3	3
GBM	AAGAB →	+0.415	+0.487	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

DTWD1 vs PDCD7 — LSCC

Explore this scatter interactively →