DTWD1

Across TCGA cell cohorts, DTWD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,743 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DTWD1-associated GO terms across cancer lineages are Circadian sleep/wake cycle, GCN2-mediated signaling, and Signal transduction in response to DNA damage. Each is linked with DTWD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both DTWD1-to-partner and partner-to-DTWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by DTWD1-low versus DTWD1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD1→partner) and Y-score (partner→DTWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Circadian sleep/wake cycle →	+0.145	+0.823	<.001	<.001	3	13
BREAST	GCN2-mediated signaling →	+0.122	+0.633	.003	.005	2	10
LARGE_INTESTINE	Signal transduction in response to DNA damage →	+0.062	+0.682	<.001	.005	3	8
BREAST	Regulation of cell cycle checkpoint →	+0.078	+0.617	.001	.001	3	8
LARGE_INTESTINE	Positive regulation of t-circle formation →	-0.100	-0.589	.005	.003	3	8
LIVER	Neuropilin signaling pathway →	+0.230	+0.753	<.001	.003	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,743 associations by consensus.

Circadian sleep/wake cycle by DTWD1 expression — PANCREAS

Explore this box plot interactively →