DTWD1

Across TCGA cell cohorts, DTWD1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DTWD1-associated genes across cancer lineages are SLC6A18 and KLRF2. Each is linked with DTWD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTWD1-to-partner and partner-to-DTWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC6A18 grouped by DTWD1-low versus DTWD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD1→partner) and Y-score (partner→DTWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SLC6A18 →	+0.034	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	KLRF2 →	+0.080	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SLC6A18 by DTWD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →