DTNB

Across TCGA patient cohorts, DTNB RNA expression is significantly associated with the protein abundance of many other proteins, with 17,545 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTNB-associated proteins across cancer lineages are SPAST, NONO, and ATP1B1. Each is linked with DTNB in more than 4 cancer types. Because this analysis shows association rather than direction, both DTNB-to-partner and partner-to-DTNB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTNB versus SPAST in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTNB→partner) and Y-score (partner→DTNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAST →	+0.678	+0.811	<.001	<.001	3	5
LSCC	NONO →	+0.204	+0.539	.002	.001	3	5
LUAD	ATP1B1 →	+0.574	+0.705	<.001	<.001	3	4
LSCC	BCL11A_S432 →	+1.319	+0.688	<.001	<.001	3	4
LSCC	BCL11A_S86 →	+1.280	+1.203	.001	<.001	3	4
LSCC	ADNP →	+0.437	+0.802	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,545 associations by consensus.

DTNB vs SPAST — LSCC

Explore this scatter interactively →