DTNA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DTNA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,816 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DTNA-associated proteins across cancer lineages are DTNA_S662, DTNA_S458, and DTNA_S564. Each is linked with DTNA in more than 7 cancer types. Because this analysis shows association rather than direction, both DTNA-to-partner and partner-to-DTNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTNA versus DTNA_S662 in CCRCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTNA→partner) and Y-score (partner→DTNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCDTNA_S662 →+1.118+0.925<.001<.00138
HNSCDTNA_S458 →+1.203+0.741<.001<.00136
OVDTNA_S564 →+1.083+1.363<.001<.00136
LUADMAP1B →+0.550+0.771<.001<.00135
HNSCMAP1B_S2271 →+0.674+0.981.003.00135
HNSCCACNA2D1 →+0.635+0.815<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,816 associations by consensus.

DTNA vs DTNA_S662 — CCRCC

Per-sample scatter of DTNA vs DTNA_S662 in CCRCC (Pearson r = 0.76).

Explore this scatter interactively →

Exploration