DTNA

Across TCGA cell cohorts, DTNA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,244 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DTNA-associated GO terms across cancer lineages are Sodium ion transmembrane transport, Regulation of translational initiation, and Potassium ion transmembrane transport. Each is linked with DTNA in more than 10 cancer types. Because this analysis shows association rather than direction, both DTNA-to-partner and partner-to-DTNA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sodium ion transmembrane transport grouped by DTNA-low versus DTNA-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTNA→partner) and Y-score (partner→DTNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Sodium ion transmembrane transport →	-0.053	-1.214	<.001	.002	3	11
OVARY	Regulation of translational initiation →	+0.078	+2.282	.002	<.001	2	11
OVARY	Potassium ion transmembrane transport →	-0.051	-1.519	<.001	<.001	3	10
PANCREAS	Ribonucleoside triphosphate biosynthetic process →	+0.085	+1.299	<.001	.003	3	10
PANCREAS	Regulation of myoblast fusion →	+0.091	+1.165	<.001	.002	3	9
OVARY	Regulation of organelle assembly →	+0.046	+2.132	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,244 associations by consensus.

Sodium ion transmembrane transport by DTNA expression — LARGE_INTESTINE

Explore this box plot interactively →