DTL

Across TCGA patient cohorts, DTL RNA expression is significantly associated with the protein abundance of many other proteins, with 24,942 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DTL-associated proteins across cancer lineages are NCAPD2, NUF2_S247, and PCNA. Each is linked with DTL in more than 9 cancer types. Because this analysis shows association rather than direction, both DTL-to-partner and partner-to-DTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTL versus NCAPD2 in GBM, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTL→partner) and Y-score (partner→DTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCAPD2 →	+0.821	+1.301	<.001	<.001	3	10
LUAD	NUF2_S247 →	+1.050	+1.067	<.001	<.001	3	10
GBM	PCNA →	+0.537	+1.127	<.001	<.001	3	10
LUAD	RFC1_T506 →	+1.210	+1.195	<.001	<.001	3	10
OV	RFC2 →	+0.417	+0.988	<.001	<.001	3	10
LSCC	RRM1 →	+0.768	+1.027	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,942 associations by consensus.

DTL vs NCAPD2 — GBM

Explore this scatter interactively →