DTL

Across TCGA patient cohorts, DTL protein abundance is significantly associated with the RNA expression of many other genes, with 12,607 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DTL-associated genes across cancer lineages are KIF14, KIF18A, and CIP2A. Each is linked with DTL in more than 6 cancer types. Because this analysis shows association rather than direction, both DTL-to-partner and partner-to-DTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTL versus KIF14 in LUAD, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTL→partner) and Y-score (partner→DTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIF14 →	+1.309	+0.958	<.001	<.001	3	7
GBM	KIF18A →	+1.368	+0.913	<.001	<.001	3	7
UCEC	CIP2A →	+0.993	+0.723	<.001	<.001	3	7
LUAD	KIF15 →	+1.142	+1.032	<.001	<.001	3	7
LUAD	BUB1 →	+1.240	+0.961	<.001	<.001	3	7
LUAD	CDKN3 →	+1.278	+0.981	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,607 associations by consensus.

DTL vs KIF14 — LUAD

Explore this scatter interactively →