Across TCGA patient cohorts, DTHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DTHD1-associated genes across cancer lineages are RIBC2, SEC14L1, and PLPPR3. Each is linked with DTHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTHD1-to-partner and partner-to-DTHD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTHD1→partner) and Y-score (partner→DTHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RIBC2 →	+1.815	+0.870	<.001	.004	3	2
LUAD	SEC14L1 →	+0.566	+0.810	<.001	<.001	3	2
UCEC	PLPPR3 →	+1.751	+0.602	<.001	.004	3	2
UCEC	WDR38 →	+2.709	+0.802	<.001	.009	3	2
UCEC	UBXN10 →	+1.477	+0.802	.001	.009	3	2
LUAD	PRR15 →	+2.821	+1.093	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,224 associations by consensus.

Exploration

DTHD1 survival (RNA) · tumor vs normal (RNA) · all DTHD1 data types