DSTYK

Across TCGA patient cohorts, DSTYK RNA expression is significantly associated with the protein abundance of many other proteins, with 20,401 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DSTYK-associated proteins across cancer lineages are RO60, NUCKS1_S19, and SEC24A. Each is linked with DSTYK in more than 6 cancer types. Because this analysis shows association rather than direction, both DSTYK-to-partner and partner-to-DSTYK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSTYK versus RO60 in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSTYK→partner) and Y-score (partner→DSTYK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RO60 →	+0.280	+0.518	<.001	<.001	3	7
HNSC	NUCKS1_S19 →	+0.476	+0.755	<.001	<.001	3	6
CCRCC	SEC24A →	-0.326	-0.411	<.001	<.001	3	6
GBM	CAMSAP2 →	+0.268	+0.304	<.001	.001	3	6
UCEC	LMNA →	+0.514	+0.395	.001	.001	3	6
LSCC	PRUNE1 →	+0.385	+0.450	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,401 associations by consensus.

DSTYK vs RO60 — BRCA

Explore this scatter interactively →