DSTYK

Across TCGA patient cohorts, DSTYK protein abundance is significantly associated with the RNA expression of many other genes, with 8,189 significant associations in total. OV shows the largest number of these associations.

The most reproducible DSTYK-associated genes across cancer lineages are PLP1, RCAN2, and DACT3. Each is linked with DSTYK in more than 2 cancer types. Because this analysis shows association rather than direction, both DSTYK-to-partner and partner-to-DSTYK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSTYK versus PLP1 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSTYK→partner) and Y-score (partner→DSTYK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLP1 →	+1.470	+0.180	<.001	<.001	3	3
UCEC	RCAN2 →	+1.075	+0.238	<.001	.003	3	3
UCEC	DACT3 →	+0.860	+0.364	<.001	<.001	3	3
UCEC	CASP12 →	+0.760	+0.250	<.001	.001	3	3
OV	CLIC1P1 →	-2.404	-0.795	<.001	.005	3	3
OV	NAP1L3 →	+1.069	+0.835	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,189 associations by consensus.

DSTYK vs PLP1 — GBM

Explore this scatter interactively →