DSTNP3

Across TCGA pan-cancer cohorts, DSTNP3 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated DSTNP3 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher DSTNP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DSTNP3 expression acts as an unfavorable survival marker, although some lineages such as LAML and LUAD show a favorable association.

LGG, LAML, and LUSC are the cancer types where DSTNP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.340	0.596	<.001	30	view →
LAML	DFS	Tertile	All	0.662	0.425	.002	30	view →
LUSC	DFS	Median	III,IV	0.374	0.895	.001	28	view →
MESO	DFS	Quartile	IV	0.126	0.634	.006	20	view →
LUAD	DFS	Quartile	All	0.811	0.636	.006	18	view →
UVM	DFS	Tertile	All	0.364	0.816	.008	14	view →
ACC	OS	Tertile	II,III,IV	0.794	0.954	.019	10	view →
CHOL	OS	Tertile	All	1.000	0.223	.010	9	view →
UCS	DFS	Tertile	II,III,IV	0.167	0.595	.016	6	view →
ESCA	DFS	Median	All	0.502	0.921	.017	6	view →
THCA	OS	Quartile	All	0.899	1.000	.024	6	view →
THYM	OS	Median	II,III,IV	0.974	0.636	.016	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

DSTNP3–LGG (OS)

Open the LGG breakdown →