DSTNP3

Across TCGA pan-cancer cohorts, DSTNP3 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DSTNP3’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where DSTNP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DSTNP3 is over-expressed in tumor, although a few such as BLCA and LUAD show the opposite, repressed pattern.

LIHC, BLCA, and LUAD are the cancer types where DSTNP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DSTNP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.437	<.001	8	view →
BLCA	All	IV	−0.802	.001	6	view →
LUAD	All	III,IV	−0.466	.007	6	view →
LUSC	All	II,III,IV	−0.429	<.001	5	view →
THCA	All	All	−0.260	<.001	5	view →
STAD	All	All	−0.732	.006	3	view →
CHOL	All	All	+0.422	.004	3	view →
KICH	All	All	−0.414	<.001	3	view →
UCEC	All	All	−0.816	<.001	2	view →
COAD	Female	All	+0.494	.022	2	view →
READ	All	III,IV	+0.480	.045	2	view →
READ	Female	All	−1.100	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DSTNP3–LIHC

Open the LIHC breakdown →