DSEL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DSEL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,866 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DSEL-associated proteins across cancer lineages are P3H3, P3H4, and SGCE. Each is linked with DSEL in more than 5 cancer types. Because this analysis shows association rather than direction, both DSEL-to-partner and partner-to-DSEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSEL versus P3H3 in COAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSEL→partner) and Y-score (partner→DSEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADP3H3 →+0.639+0.526<.001<.00136
COADP3H4 →+0.935+0.503<.001<.00136
COADSGCE →+0.780+0.524<.001<.00136
COADZCCHC24 →+0.599+0.443<.001<.00136
COADMYLK →+0.632+0.382<.001<.00135
BRCAPARVA →+0.386+0.581<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,866 associations by consensus.

DSEL vs P3H3 — COAD

Per-sample scatter of DSEL vs P3H3 in COAD (Pearson r = 0.41).

Explore this scatter interactively →

Exploration