DSEL

Across TCGA patient cohorts, DSEL protein abundance is significantly associated with the RNA expression of many other genes, with 138 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DSEL-associated genes across cancer lineages are MEFV, STAG3L4, and SUDS3. Each is linked with DSEL in more than 1 cancer types. Because this analysis shows association rather than direction, both DSEL-to-partner and partner-to-DSEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSEL versus MEFV in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSEL→partner) and Y-score (partner→DSEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEFV →	+0.691	+0.354	.005	.003	3	1
GBM	STAG3L4 →	-0.623	-0.326	.002	.006	3	1
GBM	SUDS3 →	-0.547	-0.408	.004	.001	3	1
GBM	CD274 →	+0.860	+0.350	.007	.004	3	1
GBM	KBTBD7 →	-0.615	-0.520	<.001	.001	3	1
GBM	KIRREL2 →	+1.317	+0.277	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 138 associations by consensus.

DSEL vs MEFV — GBM

Explore this scatter interactively →