DSEL

Across TCGA cell cohorts, DSEL RNA expression is significantly associated with the RNA expression of many other genes, with 6,999 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DSEL-associated genes across cancer lineages are FAT4, VGLL3, and GPR176. Each is linked with DSEL in more than 9 cancer types. Because this analysis shows association rather than direction, both DSEL-to-partner and partner-to-DSEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSEL versus FAT4 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.78.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSEL→partner) and Y-score (partner→DSEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	FAT4 →	+2.037	+2.541	<.001	<.001	3	10
SOFT_TISSUE	VGLL3 →	+2.847	+1.921	<.001	<.001	3	8
URINARY_TRACT	GPR176 →	+2.446	+0.963	<.001	.001	3	8
OESOPHAGUS	CDH2 →	+3.045	+1.251	.003	<.001	2	9
OESOPHAGUS	TENM3 →	+2.136	+0.800	<.001	.003	2	8
SOFT_TISSUE	NECTIN3 →	+2.436	+1.910	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,999 associations by consensus.

DSEL vs FAT4 — LUNG_NSCLC_LUSC

Explore this scatter interactively →