Across TCGA patient cohorts, DSCR8 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DSCR8-associated genes across cancer lineages are NTAN1P1, AQP7P5, and RNASE11. Each is linked with DSCR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both DSCR8-to-partner and partner-to-DSCR8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCR8→partner) and Y-score (partner→DSCR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NTAN1P1 →	+0.192	+5.937	.005	.002	3	1
UCEC	AQP7P5 →	+0.111	+5.694	<.001	.003	3	1
UCEC	RNASE11 →	+0.044	+6.722	<.001	<.001	3	1
UCEC	NF1P5 →	+0.229	+5.694	<.001	.003	3	1
UCEC	OR51G2 →	+0.158	+5.299	<.001	.006	3	1
UCEC	LINC01892 →	+0.210	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

DSCR8 survival (RNA) · tumor vs normal (RNA) · all DSCR8 data types