DSCR10

Across TCGA patient cohorts, DSCR10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,927 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DSCR10-associated GO terms across cancer lineages are Regulation of double-strand break repair, Mitotic DNA integrity checkpoint signaling, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with DSCR10 in more than 14 cancer types. Because this analysis shows association rather than direction, both DSCR10-to-partner and partner-to-DSCR10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by DSCR10-low versus DSCR10-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCR10→partner) and Y-score (partner→DSCR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair →	+0.058	+0.139	<.001	<.001	3	15
STAD	Mitotic DNA integrity checkpoint signaling →	+0.062	+0.138	<.001	<.001	3	15
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.075	+0.144	<.001	<.001	3	14
STAD	Mitotic spindle organization →	+0.074	+0.136	<.001	<.001	3	14
STAD	Recombinational repair →	+0.054	+0.176	<.001	<.001	3	14
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.076	+0.142	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,927 associations by consensus.

Regulation of double-strand break repair by DSCR10 expression — STAD

Explore this box plot interactively →