DSCC1

Across TCGA patient cohorts, DSCC1 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,754 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DSCC1-associated proteins across cancer lineages are RFC4, GINS3, and NCAPD2. Each is linked with DSCC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both DSCC1-to-partner and partner-to-DSCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSCC1 versus RFC4 in LSCC, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCC1→partner) and Y-score (partner→DSCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC4 →	+0.522	+0.547	<.001	<.001	3	9
GBM	GINS3 →	+0.919	+0.890	<.001	.001	3	9
LUAD	NCAPD2 →	+0.762	+0.647	<.001	<.001	3	9
BRCA	KIF22 →	+0.692	+0.749	<.001	<.001	3	8
LSCC	CHTF18 →	+0.615	+0.767	<.001	<.001	3	8
BRCA	SMC2 →	+0.752	+0.697	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,754 associations by consensus.

DSCC1 vs RFC4 — LSCC

Explore this scatter interactively →