DSCAML1

Across TCGA patient cohorts, DSCAML1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,233 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DSCAML1-associated genes across cancer lineages are ALG13, APOBEC3A, and ZNF141. Each is linked with DSCAML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DSCAML1-to-partner and partner-to-DSCAML1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSCAML1 versus ALG13 in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCAML1→partner) and Y-score (partner→DSCAML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ALG13 →	-0.320	-0.936	<.001	.001	3	2
GBM	APOBEC3A →	+0.613	+1.073	.003	<.001	3	2
GBM	ZNF141 →	-0.449	-1.043	.002	<.001	3	2
PDAC	METTL14 →	-0.255	-1.042	.005	.003	3	2
GBM	GLT1D1 →	+0.734	+0.946	.003	.003	3	2
GBM	PADI4 →	+0.400	+1.113	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,233 associations by consensus.

DSCAML1 vs ALG13 — GBM

Explore this scatter interactively →