DSCAM

Across TCGA cell cohorts, DSCAM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,313 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DSCAM-associated GO terms across cancer lineages are Microtubule-based transport, Response to platinum ion, and Cellular response to external stimulus. Each is linked with DSCAM in more than 3 cancer types. Because this analysis shows association rather than direction, both DSCAM-to-partner and partner-to-DSCAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by DSCAM-low versus DSCAM-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCAM→partner) and Y-score (partner→DSCAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Microtubule-based transport →	+0.072	+1.281	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Response to platinum ion →	-0.096	-0.496	.001	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Cellular response to external stimulus →	+0.065	+0.407	<.001	<.001	3	3
BREAST	Maintenance of postsynaptic specialization structure →	+0.116	+1.156	.002	.007	3	3
CNS	Protein histidyl modification to diphthamide →	+0.054	+0.189	.006	.004	3	3
CNS	Peptidyl-histidine modification →	+0.054	+0.189	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,313 associations by consensus.

Microtubule-based transport by DSCAM expression — LUNG_SCLC

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