DSCAM-IT1

Across TCGA patient cohorts, DSCAM-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,211 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DSCAM-IT1-associated proteins across cancer lineages are ADD1, EIF4G1, and SLC16A3. Each is linked with DSCAM-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DSCAM-IT1-to-partner and partner-to-DSCAM-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSCAM-IT1 versus ADD1 in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCAM-IT1→partner) and Y-score (partner→DSCAM-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADD1 →	+0.407	+1.361	<.001	<.001	3	3
GBM	EIF4G1 →	-0.262	-1.290	<.001	.001	3	3
GBM	SLC16A3 →	-0.660	-1.332	<.001	<.001	3	3
LSCC	KIF5C →	+0.419	+0.551	.006	.004	3	3
GBM	MVB12B →	+0.382	+2.133	<.001	<.001	3	2
HNSC	NAV3_S275 →	+0.992	+1.148	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,211 associations by consensus.

DSCAM-IT1 vs ADD1 — GBM

Explore this scatter interactively →