DSCAM-AS1

Across TCGA pan-cancer cohorts, DSCAM-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DSCAM-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where DSCAM-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DSCAM-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BRCA, LUAD, and KICH are the cancer types where DSCAM-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DSCAM-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	+2.633	<.001	6	view →
LUAD	All	All	+0.912	.003	4	view →
KICH	All	All	−0.008	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

DSCAM-AS1–BRCA

Open the BRCA breakdown →