DSC1

Across TCGA patient cohorts, DSC1 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,675 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DSC1-associated proteins across cancer lineages are ARG1, ANKRD11_S505, and CDA. Each is linked with DSC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DSC1-to-partner and partner-to-DSC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSC1 versus ARG1 in UCEC, with a Pearson correlation of 0.87.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSC1→partner) and Y-score (partner→DSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARG1 →	+1.328	+1.702	<.001	<.001	3	3
UCEC	ANKRD11_S505 →	-0.919	-2.022	<.001	<.001	3	3
UCEC	CDA →	+0.726	+1.712	.001	<.001	3	3
HNSC	DSC1_S779 →	+2.755	+1.939	<.001	<.001	3	3
LSCC	PKP1 →	+1.035	+1.057	<.001	<.001	3	3
HNSC	FAM83H →	+0.728	+1.182	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,675 associations by consensus.

DSC1 vs ARG1 — UCEC

Explore this scatter interactively →