DRP2

Across TCGA cell cohorts, DRP2 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible DRP2-associated genes across cancer lineages are CLEC14A, TRIM49D2, and NPHS2. Each is linked with DRP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRP2-to-partner and partner-to-DRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC14A grouped by DRP2-low versus DRP2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRP2→partner) and Y-score (partner→DRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CLEC14A →	+0.013	+4.217	.007	.005	3	2
STOMACH	TRIM49D2 →	+0.030	+4.285	<.001	.007	3	2
URINARY_TRACT	NPHS2 →	+0.187	+5.044	<.001	<.001	3	1
URINARY_TRACT	OPN1MW2 →	+0.015	+4.087	<.001	.009	3	1
URINARY_TRACT	DDI1 →	+0.007	+4.584	<.001	.002	3	1
URINARY_TRACT	TNP2 →	+0.010	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

CLEC14A by DRP2 expression — URINARY_TRACT

Explore this box plot interactively →