DRG2

Across TCGA patient cohorts, DRG2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,592 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DRG2-associated genes across cancer lineages are RWDD1, ECHDC1, and ZUP1. Each is linked with DRG2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DRG2-to-partner and partner-to-DRG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRG2 versus RWDD1 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRG2→partner) and Y-score (partner→DRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RWDD1 →	+0.481	+0.212	<.001	<.001	3	6
OV	ECHDC1 →	+0.832	+0.320	.002	<.001	3	6
OV	ZUP1 →	+0.578	+0.308	<.001	<.001	2	6
OV	MAN1A1 →	+1.311	+0.287	<.001	<.001	3	5
OV	CDC40 →	+0.479	+0.288	.001	.002	3	5
LSCC	STX7 →	+0.527	+0.191	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,592 associations by consensus.

DRG2 vs RWDD1 — LSCC

Explore this scatter interactively →