DRD5

Across TCGA patient cohorts, DRD5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DRD5-associated proteins across cancer lineages are GPX4, TPRG1L, and PNO1. Each is linked with DRD5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DRD5-to-partner and partner-to-DRD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRD5 versus GPX4 in LUAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD5→partner) and Y-score (partner→DRD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GPX4 →	+0.285	+0.197	<.001	<.001	3	4
GBM	TPRG1L →	+0.658	+0.271	<.001	<.001	3	3
LSCC	PNO1 →	-0.248	-0.261	.002	.007	2	4
GBM	POLR1D →	-0.348	-0.265	<.001	.003	3	3
GBM	PPP3CA →	+0.355	+0.313	<.001	<.001	3	3
GBM	QDPR →	+0.366	+0.201	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,550 associations by consensus.

DRD5 vs GPX4 — LUAD

Explore this scatter interactively →