DRD4

Across TCGA patient cohorts, DRD4 protein abundance is significantly associated with the RNA expression of many other genes, with 419 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DRD4-associated genes across cancer lineages are PLA2G3, CHADL, and CGRRF1. Each is linked with DRD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRD4-to-partner and partner-to-DRD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRD4 versus PLA2G3 in LUAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD4→partner) and Y-score (partner→DRD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLA2G3 →	+1.329	+1.266	.005	<.001	3	1
LUAD	CHADL →	+0.946	+1.461	.001	<.001	3	1
LUAD	CGRRF1 →	+0.465	+1.212	.006	.002	3	1
LUAD	SPRTN →	+0.450	+1.110	.007	.006	3	1
LUAD	RIMS4 →	+1.400	+1.659	.007	.001	3	1
LUAD	BMP7 →	+1.365	+1.500	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 419 associations by consensus.

DRD4 vs PLA2G3 — LUAD

Explore this scatter interactively →