DRD4

Across TCGA cell cohorts, DRD4 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DRD4-associated genes across cancer lineages are TBATA, CFAP299, and PRR23A. Each is linked with DRD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRD4-to-partner and partner-to-DRD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBATA grouped by DRD4-low versus DRD4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD4→partner) and Y-score (partner→DRD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TBATA →	+0.009	+4.369	<.001	.008	3	2
BLOOD_Myeloma	CFAP299 →	+0.104	+3.584	<.001	.007	3	1
BLOOD_Myeloma	PRR23A →	+0.047	+3.285	.003	.009	3	1
SOFT_TISSUE	RNASE8 →	+0.021	+4.369	<.001	.008	3	1
SOFT_TISSUE	FAM47B →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TBATA by DRD4 expression — SOFT_TISSUE

Explore this box plot interactively →