Across TCGA cell cohorts, DRD1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DRD1-associated genes across cancer lineages are C6orf118, OCM2, and ARRDC5. Each is linked with DRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRD1-to-partner and partner-to-DRD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD1→partner) and Y-score (partner→DRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.101	+3.115	.001	.004	3	1
LARGE_INTESTINE	OCM2 →	+0.047	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ARRDC5 →	+0.045	+4.505	<.001	<.001	3	1
BLOOD_Lymphoma	KRTAP9-1 →	+0.053	+6.247	<.001	<.001	3	1
LARGE_INTESTINE	CCDC168 →	+0.025	+2.878	.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

DRD1 survival (RNA) · tumor vs normal (RNA) · all DRD1 data types