DRC3

Across TCGA patient cohorts, DRC3 mutation is significantly associated with the RNA expression of many other genes, with 1,069 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DRC3-associated genes across cancer lineages are LINC02559, FAM8A2P, and MIR6815. Each is linked with DRC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DRC3-to-partner and partner-to-DRC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by DRC3-low versus DRC3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRC3→partner) and Y-score (partner→DRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	3
CESC	FAM8A2P →	+0.041	+4.539	<.001	.008	3	2
CESC	MIR6815 →	+0.533	+5.342	<.001	.002	3	2
LUAD	RNA5SP436 →	+0.608	+8.342	<.001	<.001	3	2
UCEC	RNU6-1169P →	+0.238	+2.454	.001	.004	3	2
UCEC	HMGB1P17 →	+0.243	+2.393	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,069 associations by consensus.

LINC02559 by DRC3 expression — CESC

Explore this box plot interactively →