DRAM1

Across TCGA cell cohorts, DRAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,667 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DRAM1-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Positive regulation of canonical NF-kappaB signal transduction, and Regulation of proteolysis. Each is linked with DRAM1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DRAM1-to-partner and partner-to-DRAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to abiotic stimulus grouped by DRAM1-low versus DRAM1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRAM1→partner) and Y-score (partner→DRAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular response to abiotic stimulus →	+0.048	+1.164	<.001	<.001	3	12
BONE	Positive regulation of canonical NF-kappaB signal transduction →	+0.084	+3.011	<.001	<.001	3	12
BONE	Regulation of proteolysis →	+0.159	+3.101	<.001	<.001	3	12
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.048	+1.164	<.001	<.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.147	+1.983	<.001	<.001	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.147	+1.983	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,667 associations by consensus.

Cellular response to abiotic stimulus by DRAM1 expression — LARGE_INTESTINE

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