DPYS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPYS RNA expression is significantly associated with the protein abundance of many other proteins, with 11,545 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DPYS-associated proteins across cancer lineages are GIMAP8, WAS, and CD8A. Each is linked with DPYS in more than 6 cancer types. Because this analysis shows association rather than direction, both DPYS-to-partner and partner-to-DPYS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPYS versus GIMAP8 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYS→partner) and Y-score (partner→DPYS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGIMAP8 →+0.460+0.630<.001<.00137
GBMWAS →+0.375+0.277<.001<.00136
OVCD8A →+0.837+0.583<.001<.00136
LSCCDOCK2 →+0.531+0.411<.001.00136
OVEPB41L3 →+0.783+0.688<.001<.00136
GBMFOLR2 →+0.938+0.374<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,545 associations by consensus.

DPYS vs GIMAP8 — OV

Per-sample scatter of DPYS vs GIMAP8 in OV (Pearson r = 0.49).

Explore this scatter interactively →

Exploration