DPYS

Across TCGA cell cohorts, DPYS RNA expression is significantly associated with the go_rna of many other GO terms, with 870 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DPYS-associated GO terms across cancer lineages are Vacuole organization, Nuclear envelope organization, and Protein localization to membrane raft. Each is linked with DPYS in more than 4 cancer types. Because this analysis shows association rather than direction, both DPYS-to-partner and partner-to-DPYS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by DPYS-low versus DPYS-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYS→partner) and Y-score (partner→DPYS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vacuole organization →	+0.037	+0.183	.003	.007	3	5
LUNG_SCLC	Nuclear envelope organization →	+0.051	+0.261	.003	.003	3	5
SKIN	Protein localization to membrane raft →	-0.220	-0.305	<.001	.006	3	4
SKIN	Contractile actin filament bundle assembly →	-0.118	-0.391	<.001	.003	3	4
SKIN	Subtelomeric heterochromatin formation →	+0.069	+0.289	.003	.003	3	4
SKIN	Microtubule anchoring →	+0.057	+0.224	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 870 associations by consensus.

Vacuole organization by DPYS expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →