DPY30

Across TCGA patient cohorts, DPY30 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPY30-associated genes across cancer lineages are SERPINA15P, CTBP2P10, and NUTF2P8. Each is linked with DPY30 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPY30-to-partner and partner-to-DPY30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA15P grouped by DPY30-low versus DPY30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY30→partner) and Y-score (partner→DPY30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SERPINA15P →	+0.195	+4.727	<.001	.003	3	2
COAD	CTBP2P10 →	+0.024	+7.741	<.001	.009	3	1
UCEC	NUTF2P8 →	+0.172	+3.567	<.001	.005	3	1
BLCA	RNU6-478P →	+0.333	+7.640	<.001	.009	3	1
UCEC	MIR3928 →	+0.636	+3.386	<.001	.008	3	1
UCEC	MIR5696 →	+0.520	+4.708	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

SERPINA15P by DPY30 expression — UCEC

Explore this box plot interactively →