DPY30

Across TCGA cell cohorts, DPY30 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,849 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DPY30-associated GO terms across cancer lineages are Regulation of cardiolipin metabolic process, Pigment metabolic process involved in pigmentation, and Angiogenesis. Each is linked with DPY30 in more than 7 cancer types. Because this analysis shows association rather than direction, both DPY30-to-partner and partner-to-DPY30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiolipin metabolic process grouped by DPY30-low versus DPY30-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY30→partner) and Y-score (partner→DPY30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of cardiolipin metabolic process →	+0.149	+0.510	<.001	<.001	3	8
LUNG_SCLC	Pigment metabolic process involved in pigmentation →	-0.255	-0.604	.001	<.001	3	8
LUNG_NSCLC_LUAD	Angiogenesis →	-0.036	-0.392	.005	.001	2	8
URINARY_TRACT	Extracellular matrix organization →	-0.094	-0.597	<.001	<.001	3	7
URINARY_TRACT	Extracellular structure organization →	-0.094	-0.597	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	External encapsulating structure organization →	-0.098	-0.624	.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,849 associations by consensus.

Regulation of cardiolipin metabolic process by DPY30 expression — SKIN

Explore this box plot interactively →