DPY19L3

Across TCGA cell cohorts, DPY19L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,156 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DPY19L3-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and Stress granule assembly. Each is linked with DPY19L3 in more than 16 cancer types. Because this analysis shows association rather than direction, both DPY19L3-to-partner and partner-to-DPY19L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by DPY19L3-low versus DPY19L3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L3→partner) and Y-score (partner→DPY19L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of DNA repair →	+0.088	+1.325	<.001	<.001	3	17
OVARY	Positive regulation of double-strand break repair →	+0.094	+1.101	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.114	+0.920	<.001	<.001	3	15
STOMACH	Negative regulation of gene expression, epigenetic →	+0.101	+1.547	<.001	<.001	3	15
LUNG_SCLC	Golgi vesicle transport →	+0.062	+0.928	<.001	<.001	3	15
BONE	Positive regulation of DNA metabolic process →	+0.069	+0.718	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,156 associations by consensus.

Positive regulation of DNA repair by DPY19L3 expression — STOMACH

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