DPY19L3

Across TCGA cell cohorts, DPY19L3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPY19L3-associated genes across cancer lineages are PFN3, CRISP1, and C16orf96. Each is linked with DPY19L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPY19L3-to-partner and partner-to-DPY19L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PFN3 grouped by DPY19L3-low versus DPY19L3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L3→partner) and Y-score (partner→DPY19L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PFN3 →	+0.081	+4.450	<.001	.004	3	1
LARGE_INTESTINE	CRISP1 →	+0.012	+3.678	<.001	.001	3	1
LARGE_INTESTINE	C16orf96 →	+0.454	+3.743	.006	.001	3	1
LUNG_SCLC	OXT →	+0.303	+3.736	.002	.007	3	1
LUNG_SCLC	SLC2A7 →	+0.412	+3.710	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PFN3 by DPY19L3 expression — OVARY

Explore this box plot interactively →