DPY19L1P1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DPY19L1P1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated DPY19L1P1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher DPY19L1P1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DPY19L1P1 expression acts as an unfavorable survival marker.

ESCA and SKCM are the cancer types where DPY19L1P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCADFSMedianAll0.1460.533.0463view →
SKCMOSMedianAll0.6860.788.0432view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DPY19L1P1–ESCA (DFS)

Kaplan–Meier survival curve for DPY19L1P1 mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration