DPY19L1P1

Across TCGA pan-cancer cohorts, DPY19L1P1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of DPY19L1P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DPY19L1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DPY19L1P1 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

HNSC, KIRC, and COAD are the cancer types where DPY19L1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DPY19L1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	All	+0.698	<.001	11	view →
KIRC	Male	IV	+0.684	<.001	11	view →
COAD	Male	All	+0.891	<.001	9	view →
LIHC	Male	II,III,IV	+0.759	<.001	9	view →
KIRP	All	All	+0.548	<.001	9	view →
LUAD	Male	All	+0.790	<.001	8	view →
BLCA	All	All	+0.525	.011	6	view →
BRCA	Female	All	−0.320	<.001	6	view →
STAD	All	All	+0.635	<.001	5	view →
PAAD	All	All	+1.042	<.001	4	view →
CHOL	All	All	+1.377	<.001	3	view →
ESCA	All	All	+0.851	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

DPY19L1P1–HNSC

Open the HNSC breakdown →