DPPA4

Across TCGA patient cohorts, DPPA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,085 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DPPA4-associated GO terms across cancer lineages are B cell activation involved in immune response, Type I interferon production, and mRNA transport. Each is linked with DPPA4 in more than 19 cancer types. Because this analysis shows association rather than direction, both DPPA4-to-partner and partner-to-DPPA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell activation involved in immune response grouped by DPPA4-low versus DPPA4-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA4→partner) and Y-score (partner→DPPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	B cell activation involved in immune response →	+0.071	+0.156	<.001	.001	2	20
SCLC	Type I interferon production →	+0.094	+0.185	<.001	<.001	3	19
STAD	mRNA transport →	+0.078	+0.265	<.001	<.001	3	19
STAD	Positive regulation of mRNA metabolic process →	+0.066	+0.277	<.001	<.001	3	19
STAD	Regulation of DNA recombination →	+0.062	+0.283	<.001	<.001	3	18
STAD	Cytoplasmic pattern recognition receptor signaling pathway →	+0.069	+0.278	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,085 associations by consensus.

B cell activation involved in immune response by DPPA4 expression — SCLC

Explore this box plot interactively →