DPPA4

Across TCGA cell cohorts, DPPA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 193 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible DPPA4-associated GO terms across cancer lineages are Negative regulation of intracellular steroid hormone receptor signaling pathway, Regulation of RNA splicing, and Vesicle-mediated transport between endosomal compartments. Each is linked with DPPA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPPA4-to-partner and partner-to-DPPA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of intracellular steroid hormone receptor signaling pathway grouped by DPPA4-low versus DPPA4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA4→partner) and Y-score (partner→DPPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of intracellular steroid hormone receptor signaling pathway →	+0.066	+0.017	.001	.004	3	3
PANCREAS	Regulation of RNA splicing →	+0.071	+0.012	<.001	.009	3	3
PANCREAS	Vesicle-mediated transport between endosomal compartments →	+0.048	+0.009	.003	.007	3	2
KIDNEY	Transcription elongation-coupled chromatin remodeling →	+0.064	+0.027	.005	.002	3	2
KIDNEY	Autocrine signaling →	-0.181	-0.036	.003	.003	3	2
KIDNEY	Xenobiotic metabolic process →	-0.078	-0.028	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

Negative regulation of intracellular steroid hormone receptor signaling pathway by DPPA4 expression — PANCREAS

Explore this box plot interactively →