DPPA3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPPA3 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DPPA3-associated genes across cancer lineages are INPP4B, PCNA, and PDCD4. Each is linked with DPPA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPPA3-to-partner and partner-to-DPPA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA3→partner) and Y-score (partner→DPPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.313-2.999.045.03532
UCECPCNA →+0.225+2.321.031.03432
UCECPDCD4 →-0.522-2.459.021.02032
SKCMCyclin-E1 →+0.233+3.169.038.01832
UCECmTOR_pS2448 →-0.145-2.980.044.03631
UCECSrc_pY416 →-0.273-3.571.019.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration