DPPA2

Across TCGA patient cohorts, DPPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,828 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DPPA2-associated GO terms across cancer lineages are Mitochondrial translation, Regulation of protein localization to chromosome, telomeric region, and Mitochondrial membrane organization. Each is linked with DPPA2 in more than 13 cancer types. Because this analysis shows association rather than direction, both DPPA2-to-partner and partner-to-DPPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by DPPA2-low versus DPPA2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA2→partner) and Y-score (partner→DPPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial translation →	+0.080	+0.436	<.001	<.001	3	14
STAD	Regulation of protein localization to chromosome, telomeric region →	+0.078	+0.325	<.001	<.001	3	13
STAD	Mitochondrial membrane organization →	+0.072	+0.367	<.001	<.001	3	13
STAD	tRNA metabolic process →	+0.069	+0.395	<.001	<.001	3	13
STAD	RNA localization →	+0.076	+0.364	<.001	<.001	3	13
STAD	RNA export from nucleus →	+0.078	+0.358	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,828 associations by consensus.

Mitochondrial translation by DPPA2 expression — STAD

Explore this box plot interactively →