DPP9

Across TCGA cell cohorts, DPP9 mutation is significantly associated with the RNA expression of many other genes, with 239 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPP9-associated genes across cancer lineages are NDUFB10, OR7E24, and KRTAP5-4. Each is linked with DPP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPP9-to-partner and partner-to-DPP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFB10 grouped by DPP9-low versus DPP9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP9→partner) and Y-score (partner→DPP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NDUFB10 →	+0.527	+3.212	.001	.006	3	2
SOFT_TISSUE	OR7E24 →	+0.022	+4.369	<.001	.008	3	1
SOFT_TISSUE	KRTAP5-4 →	+0.024	+4.369	<.001	.008	3	1
BLOOD_Myeloma	NWD2 →	+0.006	+3.716	<.001	.005	3	1
BLOOD_Myeloma	LCE5A →	+0.060	+4.321	<.001	<.001	3	1
BLOOD_Myeloma	OR2L13 →	+0.056	+3.584	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 239 associations by consensus.

NDUFB10 by DPP9 expression — LARGE_INTESTINE

Explore this box plot interactively →