DPP8

Across TCGA patient cohorts, DPP8 protein abundance is significantly associated with the RNA expression of many other genes, with 10,087 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DPP8-associated genes across cancer lineages are RCC1, WDR61, and GUCY1A2. Each is linked with DPP8 in more than 4 cancer types. Because this analysis shows association rather than direction, both DPP8-to-partner and partner-to-DPP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPP8 versus RCC1 in BRCA, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP8→partner) and Y-score (partner→DPP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RCC1 →	-0.728	-0.271	<.001	<.001	3	5
LSCC	WDR61 →	+0.328	+0.184	.006	.003	3	4
UCEC	GUCY1A2 →	+1.108	+0.153	<.001	<.001	3	4
BRCA	NPTN →	+0.601	+0.214	<.001	<.001	3	4
UCEC	CCDC80 →	+1.012	+0.142	.002	.001	3	4
BRCA	APH1B →	+0.704	+0.243	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,087 associations by consensus.

DPP8 vs RCC1 — BRCA

Explore this scatter interactively →