DPP4-DT

Across TCGA pan-cancer cohorts, DPP4-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DPP4-DT data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher DPP4-DT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DPP4-DT expression acts as an unfavorable survival marker, although some lineages such as LUAD and THCA show a favorable association.

STAD, BLCA, and LGG are the cancer types where DPP4-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	All	0.233	0.471	.002	73	view →
BLCA	DFS	Median	II,III,IV	0.457	0.557	.005	47	view →
LGG	DFS	Median	All	0.759	0.867	<.001	44	view →
LUAD	OS	Median	III,IV	0.764	0.551	.004	43	view →
DLBC	DFS	Quartile	All	0.241	1.000	.001	40	view →
THCA	OS	Median	All	0.988	0.894	<.001	40	view →
ACC	DFS	Quartile	III,IV	0.186	0.609	.003	39	view →
MESO	OS	Median	IV	0.838	0.313	.001	27	view →
HNSC	DFS	Tertile	All	0.646	0.453	.018	14	view →
COAD	DFS	Median	II,III,IV	0.331	0.567	.011	14	view →
CESC	DFS	Median	II,III,IV	0.720	0.416	.031	12	view →
KIRP	OS	Tertile	II,III,IV	1.000	0.210	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

DPP4-DT–STAD (OS)

Open the STAD breakdown →